The area to be treated will be thoroughly cleansed to allow for better penetration of the topical agent. The photosensitizing cream is then applied to the entire surface area of the skin that requires treatment and will be allowed to absorb for several hours.
Then it will be activated by a specific-wavelength light, which will produce a form of oxygen that kills the cancer cells. PDT selectively destroys the targeted skin cancer cells while causing only minimal damage to the surrounding tissues. It has the added benefit of damaging the blood vessels feeding the cancer cells, and alerting the immune system to attack those cells.

The skin treated will be extremely light-sensitive for 48 hours until the topical agent is completely metabolised. For the first 2–3 days, there will be some redness and mild peeling. Occasionally, there can be a burning sensation for up to 24 hours after the procedure, and prolonged redness and peeling lasting 5–14 days. It is advisable to wear protective hats, clothing and thick sunblock containing zinc during this period of sensitivity along with exercising sun avoidance where at all possible.

Treatment usually needs to be repeated in 2 weeks to ensure the highest chance of cure.

You will be quoted the out-of-pocket costs as Medicare does not provide a rebate for PDT.